Precision Compound Analysis for Demanding Laboratory Applications

Chem Test Guru’s HPLC solutions deliver high-resolution separation and quantification for critical applications across life sciences, pharmaceuticals, and more.

High-Performance Liquid Chromatography (HPLC) is an essential analytical technique used to separate, identify, and quantify components in liquid mixtures with unmatched precision. Renowned for its ability to handle complex compound analysis, HPLC plays a vital role in ensuring quality, purity, and compliance in research and production environments alike. From clinical laboratories to food safety labs and pharmaceutical development, HPLC offers unmatched consistency and reliability. At Chem Test Guru, we provide industry-leading HPLC systems tailored for both routine and advanced applications. Headquartered in New York, NY, we’ve built a reputation for delivering reliable, innovative solutions that help businesses across the U.S. and Canada streamline their operations. Our customers benefit from technological expertise, ongoing product development, and responsive support that sets us apart in the analytical instrumentation space.

The Following are Our Advanced Offerings for High-Performance Liquid Chromatography (HPLC) Systems

In addition to offering products and systems developed by us and our other partners, we are proud to carry top-tier solutions from our trusted partners, GAO Tek Inc. These partnerships enable us to deliver reliable, high-quality technologies, integration, and services you can count on. Where appropriate, we have provided links to relevant products and systems from GAO Tek Inc.

Core Components of Our HPLC Systems

Hardware

  • Solvent Delivery System (Pump): Temperature & Process Calibrators ensure accurate thermal conditions for teaching flow consistency in solvent systems.
  • Autosampler: Sound Level Meters & Calibrators help monitor operational noise during automated sampling in classroom demonstrations.
  • Column Compartment: Infrared Thermometers & Cameras allow students to visualize and control thermal zones within chromatographic columns.
  • Detector (UV, PDA, FLD, etc.): Refractometers assist in teaching compound detection and identification through light interaction principles.
  • Data Acquisition Software: Carbon Monoxide Gas Detector provides real-time environmental data integration for air quality education in software-based monitoring setups.

Software

  • Empower CDS
  • OpenLAB CDS
  • Chromeleon CDS
  • LabSolutions
  • MassHunter

Cloud Services

  • Waters Connect
  • Agilent SLIMS
  • Thermo Fisher Connect
  • Sciex OS Cloud
  • Benchling

Key Features

  • High Separation Efficiency: Delivers accurate results with sharp peak resolution, even in complex mixtures.
  • Multi-Detector Compatibility: Supports UV/Vis, Photodiode Array (PDA), Refractive Index (RI), Fluorescence, and Mass Spectrometry.
  • Gradient Elution Capability: Enables the analysis of diverse sample types with improved separation performance.
  • Thermos tatted Column Control: Ensures consistent retention times and reproducibility.
  • Automated Sample Handling: Increases throughput while reducing human error.
  • User-Friendly Software Interface: Streamlines method development, calibration, and data reporting.

Common Use Cases

  • Pharmaceutical Quality Control and R&D
  • Biochemical and Clinical Research
  • Environmental Pollutant Analysis
  • Food and Beverage Testing
  • Cosmetic and Personal Care Product Analysis
  • Cannabis Potency and Contaminant Screening

Integrations & Ecosystem Compatibility

  • Compatible with Mass Spectrometry (LC-MS) systems for advanced molecular identification
  • Integration-ready with LIMS (Laboratory Information Management Systems)
  • Fully compliant with FDA 21 CFR Part 11, GLP, and cGMP standards
  • API and software integration available for custom lab automation

Industries Served

  • Restaurant and Food Service Industry
  • Retail and Supermarkets
  • Food Research and Development
  • Regulatory and Quality Assurance Agencies

Relevant U.S. & Canadian Standards & Regulations

  • 21 CFR Part 11 (U.S. FDA)
  • USP <621> Chromatography
  • EPA Method 8310
  • Health Canada GMP Guidelines
  • ISO/IEC 17025

Benefits of Choosing Chem Test Guru’s HPLC Systems

  • Reliable Performance: Our HPLC systems undergo strict quality assurance protocols for dependable long-term use.
  • Customizable Configurations: Tailored setups to match your specific analysis needs.
  • Scalable Solutions: From single-lab setups to enterprise-scale operations, our systems grow with you.
  • Expert Support: Access to dedicated technical consultants for system installation, training, and troubleshooting.
  • Innovation-Driven: Backed by cutting-edge research and continuous product development, our systems are designed to keep you ahead of industry demands.

Applications

  • Quantitative and qualitative analysis of complex mixtures
  • Identification of unknown compounds in a sample
  • Purity analysis of pharmaceuticals and fine chemicals
  • Monitoring degradation and stability of drugs
  • Measuring concentrations of bioactive molecules
  • Separation of enantiomers in chiral compounds
  • Screening for banned substances in competitive sports and agriculture

Case Studies

Case Study 1: Pharmaceutical Quality Control

A major pharmaceutical company in New Jersey implemented HPLC systems to enhance quality control across multiple production lines. Using gradient and reverse-phase HPLC methods, they successfully improved the detection accuracy of impurities in active pharmaceutical ingredients (APIs), reducing batch rejection rates by 35% and ensuring compliance with FDA regulations.

Case Study 2: Food Safety Testing in Beverage Manufacturing

A global beverage brand used HPLC to monitor caffeine and preservative levels across its energy drink product line. By adopting automated HPLC analysis, the company reduced testing time by 50% and improved regulatory reporting efficiency, ensuring alignment with international food safety standards.

Case Study 3: Environmental Lab Enhances Pesticide Detection

An environmental lab in California adopted HPLC systems to measure trace levels of pesticide residues in soil and groundwater. With sensitive UV and mass spectrometry detectors, the lab achieved sub-ppb level detection and met stringent EPA requirements for agricultural site monitoring.

Case Study 4: Clinical Lab Optimizes Therapeutic Drug Monitoring

A hospital laboratory integrated HPLC into its therapeutic drug monitoring workflow to quantify plasma drug concentrations in transplant patients. The accurate, real-time data helped doctors adjust dosages more effectively, reducing adverse reactions by 22% over a six-month period.

Case Study 5: Academic Research in Natural Product Chemistry

A university research group studying plant-based compounds used HPLC for compound isolation and structural elucidation. Their published findings in peer-reviewed journals were enabled by high-resolution chromatographic data and reproducibility of retention times, enhancing the credibility of their research.

Contact Us

Need help finding the right chemical tester for your operations?
Our team is here to assist with personalized recommendations, product support, and expert guidance.  Contact Us to speak with a Chem Test Guru representative today.